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On this part, Callen and Berkowitz elaborate on the multifactorial mannequin to provide a basis for later functions of protected sex practices. At the time when How one can Have Sex in an Epidemic was written, there was no consensus on the reason for AIDS, but two foremost theories existed: the "new agent concept," which was more and more the scientific consensus, and the "multifactorial theory," which Callen, Berkowitz and Sonnabend adopted as their foundation for sexual education around AIDS transmission prevention. The authors introduce the 2 presiding theories of AIDS transmission and current their arguments for the multifactorial model. Although the multifactorial model had been criticized for failing to account for the sudden look of AIDS, the authors use the fact that the rate of CMV infections in city sexually lively gay men rose significantly in last decade as proof of the "new" part that accounts for the rapid enhance in AIDS cases. As David France later recounted, the authors actively tried to keep away from condescension or arrogance of their writing (despite the fact that Callen himself had acknowledged that telling folks find out how to have sex is inherently an arrogant thing to do), instead trying to establish a dialogue, "queen to queen," between themselves and the people for whom they created the guide.